Biostatistics Core

The Biostatistics Core will provide high quality, efficient, integrated collaboration in, and support of, the proposed UMN Udall Center on Deep Brain Stimulation (DBS) for Parkinson’s Disease (PD). The overall theme of the Center is to develop novel, circuit-based DBS therapies for PD. As a foundation for all four proposed projects, and in collaboration with other cores in support of this foundation, this Core will provide: personnel with the appropriate breadth and depth of expertise for the motor, neurophysiological, cognitive, and smartphone/telemedicine data being collected; services in study design, robust and reproducible data management and quality control pipelines, statistical and machine learning analysis, and interpretation and communication; data integration across the many types of data being collected and data sharing with the NINDS Parkinson’s Disease Biomarkers Program (PDBP) Data Management Resource (DMR); career development related to proficiency in statistical and machine learning approaches, study design concepts, and communication on interdisciplinary teams for investigators, post-docs, and students in the Center; participation in engagement and dissemination activities; and other resources as needed.